Oxcarbazepine Adjunctive Therapy for Partial Seizures
نویسندگان
چکیده
منابع مشابه
Lacosamide adjunctive therapy for partial-onset seizures: a meta-analysis
Background. The relative efficacy and safety of lacosamide as adjunctive therapy compared to other antiepileptic drugs has not been well established. Objective. To determine if lacosamide provides improved efficacy and safety, reduced length of hospital stay and improved quality of life compared with other anti-epileptic therapies for adults with partial-onset seizures. Data Sources. A systemat...
متن کاملAdjunctive perampanel for refractory partial-onset seizures
Methods: This was a multicenter, double-blind, placebo-controlled trial (ClinicalTrials.gov identifier: NCT00699972). Patients ( 12 years, with ongoing seizures despite 1–3 AEDs) were randomized (1:1:1) to once-daily perampanel 8 mg, 12 mg, or placebo. Following baseline (6 weeks), patients entered a 19-week double-blind phase: 6-week titration (2 mg/week increments to target dose) followed by ...
متن کاملrosa damascena oil: an adjunctive therapy for pediatric refractory seizures
objective several investigations have demonstrated that rosa damascena has an inhibitory effect on the hypothalamus and on pituitary system reactivity in the rat; it has also been shown that the essential oil of rosa damascena has significant antiepileptic effects on pentylentetrazole (ptz) induced seizures in rats. we aimed at assessing the effects of the essential oil of rosa damascena when u...
متن کاملLong‐term efficacy and safety of adjunctive extended‐release oxcarbazepine (Oxtellar XR®) in adults with partial‐onset seizures
OBJECTIVE To evaluate long-term outcomes of adjunctive therapy with SPN-804 (Oxtellar XR® , Supernus Pharmaceuticals), an extended-release tablet formulation of oxcarbazepine (OXC), in adults with refractory partial-onset seizures. METHODS After completing a 16-week double-blind, placebo-controlled trial of SPN-804 at fixed dosages (1200 or 2400 mg QD), patients entering this open-label exten...
متن کاملHealth Technology Assessment of Lacosamide as Adjunctive Therapy for Partial-Onset Epileptic Seizures
Epilepsy is a neurological disorder that disrupts the normal transmission of electrical signals in the brain and is characterised by abnormal electrical neuronal activity resulting clinically in unprovoked recurring seizures. Partial-onset seizures are those that involve only a portion of the brain at seizure onset. The prevalence of epilepsy varies between 4 and 8 cases per 1,000 individuals i...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2000
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-14-7-6